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Low nickel diet: an open, prospective trial
N K Veien1, T Hattel, G Laurberg
1Dermatology Clinic, Aalborg, Denmark.
Journal of the American Academy of Dermatology
|December 1, 1993
Summary
Reducing dietary nickel intake can improve dermatitis for some nickel-sensitive individuals. A low-nickel diet offered short-term and long-term benefits for many patients with nickel allergy.
Area of Science:
- Dermatology
- Allergology
- Nutritional Science
Background:
- Nickel-sensitive individuals often experience persistent dermatitis despite avoiding skin contact with nickel.
- Identifying triggers beyond direct contact is crucial for managing nickel allergy.
Purpose of the Study:
- To investigate if reducing dietary nickel intake alleviates dermatitis symptoms in nickel-sensitive patients.
- To assess the efficacy of a low-nickel diet in managing nickel allergy-related skin conditions.
Main Methods:
- Ninety nickel-sensitive patients with dermatitis flares after oral nickel challenge were enrolled.
- Participants followed a low-nickel diet, and outcomes were monitored for short-term and long-term improvement.
Main Results:
- 58% of patients showed short-term benefit from the low-nickel diet, with 15 others experiencing possible improvement.
- Long-term follow-up (1-2 years) indicated sustained dermatitis improvement in 40 out of 55 compliant patients.
- Patients with less severe nickel sensitivity (moderately positive patch tests) reported greater dietary benefit.
Conclusions:
- Lowering dietary nickel intake can be an effective strategy for managing dermatitis in some nickel-sensitive patients.
- The study suggests a link between dietary nickel and dermatitis activity, supporting dietary modification as a therapeutic option.