[Monocyte aggregation as a criterion in the evaluation of mononuclear phagocytes function in patients with bronchial...

The study was made of arachidonate-induced aggregation of peripheral blood monocytes in 18 patients with bronchial asthma versus 12 controls. Monocytic aggregation and dependence of the patients on glucocorticosteroids appeared related: in hormones untreated patients the aggregation was more active than in controls. The aggregation of hormone-dependent patients and controls showed no significant differences. Allergic reaction correlated in severity to aggregation intensity. The method of graphic registration of arachidonate-induced aggregation of peripheral blood monocytes is promising in evaluation of immunity macrophagal-monocytic component in asthmatic patients.