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Updated: Jul 20, 2026

An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis
Published on: February 8, 2019
Multiple central giant cell lesions with a Noonan-like phenotype
N J Betts1, J C Stewart, R J Fonseca
1Department of Oral and Maxillofacial Surgery, University of Pennsylvania School of Dental Medicine, Philadelphia.
Abstract:
A small number of patients with the phenotypic features of Noonan syndrome have also developed giant cell lesions of the jaws similar to those seen in cherubism. This case report describes an individual with the features of the recently described Noonan-like/multiple giant cell lesion syndrome. Previously reported cases and issues relative to diagnosis and management are considered.
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