Related Experiment Videos
Photochemical cleavage of DNA by phosphorus(V) porphyrin derivatives
T Saito1, M Kitamura, M Tanaka
1Division of Molecular Engineering, Graduate School of Engineering, Kyoto University, Japan.
Nucleic Acids Symposium Series
|January 1, 1993
Abstract:
Photocleavages of double-stranded circular DNA and oligonucleotide were investigated by the use of phosphorus(V)tetraphenylporphyrin (P(V)TPP) derivatives. The P(V)TPP derivatives cleaved the DNA and the oligonucleotide under the visible light irradiation, in air and in argon, respectively. It is suggested that the photocleavage reactions include an electron transfer mechanism as well as a singlet oxygen (1O2) one.