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Physiology and pathophysiology of gallbladder motility
S Tierney1, H A Pitt, K D Lillemoe
1Department of Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland.
The Surgical Clinics of North America
|December 1, 1993
Summary
Gallbladder stasis is linked to most gallbladder diseases. Understanding gallbladder motility is key for diagnosing and treating conditions like chronic acalculous cholecystitis.
Area of Science:
- Gastroenterology and Hepatology
- Physiology
Background:
- Gallbladder stasis is a primary factor in significant gallbladder diseases.
- Gallbladder motility is regulated by intricate hormonal and neural mechanisms.
Purpose of the Study:
- To explore the role of gallbladder motility in gallstone disease.
- To highlight the clinical significance of measuring gallbladder motility.
Main Methods:
- Review of experimental and clinical studies on gallbladder motility.
- Analysis of diagnostic and therapeutic advancements in gallbladder disease.
Main Results:
- Impaired gallbladder motility is evident in gallstone disease.
- Motility disturbances appear to precede gallstone formation.
Conclusions:
- Gallbladder motility is crucial in gallstone pathogenesis.
- Clinical assessment of gallbladder motility improves diagnosis and treatment of chronic acalculous cholecystitis.