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Nonsteroidal antiinflammatory drug desensitization using flurbiprofen (Ansaid)
D M Douglas1, L Ward, J S Brown
1Department of Internal Medicine, Madigan Army Medical Center, Tacoma, Washington.
Annals of Allergy
|November 1, 1993
Summary
Hypersensitivity to nonsteroidal anti-inflammatory drugs (NSAIDs) is common. This study details successful desensitization to flurbiprofen, a newer NSAID, using incremental oral challenges in a patient with known NSAID reactions.
Area of Science:
- Immunology
- Pharmacology
- Rheumatology
Background:
- Reactions to nonsteroidal anti-inflammatory drugs (NSAIDs) and aspirin are frequent occurrences.
- Cross-reactivity and sensitization are common issues within the NSAID class.
- Developing standardized approaches for NSAID use in hypersensitive patients is ongoing.