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Biosensor for direct determination of glucose and lactate in undiluted biological fluids
L Campanella1, M Tomassetti, F Mazzei
1Dipartimento di Chimica, Universitá La Sapienza, Roma, Italy.
Biosensors & Bioelectronics
|January 1, 1993
Abstract:
This paper describes the implementation of a bienzyme sensor for the direct determination of glucose and lactate in undiluted biological samples. The biosensor exploits the competitive action versus the substrate itself by two different enzymes immobilized into a sandwich of two different membranes. In this way the quantity of substrate reaching the indicating electrode is reduced and this determines an extension of the linearity range.
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