[Recent aspects in diagnosis and therapy of esophageal varices]

Esophageal varices are of ominous significance in patients with cirrhosis. Diagnostic procedures are undertaken for evaluation of the bleeding risk. Whereas after a recent bleeding event the risk of rebleeding is high (up to 70%) and rebleeding prophylaxis is obligatory, the risk of first bleeding in patients who never bled depends on the presence of bleeding risk indicators. Endoscopy is the most powerful tool for assessment of the bleeding risk. Variceal size, the presence of the red color sign and the presence of concomitant fundic varices indicate a high risk of first bleeding. Currently used endoscopic or medical prophylaxis has a high rate of failure. On the other hand, operative measures prevent bleeding in most patients. However, the perioperative morbidity and mortality is high. Controlled studies will show whether the patients will benefit from new experimental treatment approaches (endoscopic obliteration of varices, endoscopic ligation of varices, TIPS and liver transplantation.