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Related Experiment Videos

Bone mass measurement: how, where, when and why?

P D Delmas1

  • 1Claude Bernard University of Lyon, France.

International Journal of Fertility and Menopausal Studies
|January 1, 1993
PubMed
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Low bone mass is a key factor in osteoporotic fractures and cannot be predicted by clinical risk factors alone. Bone densitometry methods like DXA are essential for accurate diagnosis and fracture risk assessment.

Area of Science:

  • Osteoporosis research
  • Bone densitometry
  • Fracture risk assessment

Background:

  • Low bone mass is the primary cause of osteoporotic fractures.
  • Clinical risk factor evaluation is insufficient for predicting fracture risk.
  • Accurate bone mass measurement is crucial for osteoporosis management.

Purpose of the Study:

  • To review current methods for bone mass measurement.
  • To discuss the clinical utility of bone densitometry.
  • To evaluate the predictive value of bone mass measurements for osteoporotic fractures.

Main Methods:

  • Dual-energy X-ray absorptiometry (DXA) is the current standard.
  • Quantitative Computed Tomography (QCT) and ultrasound methods are also discussed.
  • Comparison of practical and technical aspects of different bone densitometry techniques.

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Main Results:

  • DXA is widely used and can measure bone mass at various skeletal sites.
  • Bone mass measurement is useful in specific clinical situations, such as postmenopausal women and patients with vertebral deformities.
  • A decrease of 1 standard deviation in bone mass increases fracture risk 1.5- to 3-fold.

Conclusions:

  • Bone densitometry is essential for diagnosing osteoporosis and assessing fracture risk.
  • DXA is a versatile tool for measuring bone mass at multiple sites.
  • Hip bone mass measurement is a strong predictor of hip fracture risk.