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Meningomyelocele associated with cranium bifidum: rare coexistence of two major malformations
Abstract:
Three cases of lumbosacral meningomyelocele associated with cranium bifidum are reported. The meningomyeloceles were of the neural placode type and the cranium bifidum was an interfrontal encephalomeningocele in all cases. Two of the patients received ventriculoperitoneal shunts and had evidence of type II Chiari malformation on magnetic resonance imaging. No evidence of a Chiari malformation was revealed in the third patient. We discuss the etiology of the rare coexistence of these two major malformations.
Insights
This study reports three cases of neural placode-type lumbosacral meningomyelocele associated with interfrontal encephalomeningocele (cranium bifidum). Two patients had Chiari malformation type II, while one did not, prompting discussion on the etiology of this rare dual malformation.
Area of Science:
- Developmental Biology
- Neuroscience
- Pediatric Surgery
Background:
- Lumbosacral meningomyelocele and cranium bifidum are significant congenital malformations.
- The simultaneous occurrence of these two conditions, specifically neural placode-type meningomyelocele and interfrontal encephalomeningocele, is exceptionally rare.
- Understanding the underlying etiology is crucial for diagnosis and management.
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