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[Synthesis and antimicrobial properties of methyl 3-O-alkyl-glucopyranosides]
1Department of Pharmacy, Kitasato University Hospital, School of Hygienic Science, Sagamihara, Japan.
Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan
|October 1, 1993
Abstract:
A new type of nonionic surface-active agents containing sugars as the hydrophilic group were synthesized and evaluated for their antimicrobial activity. Methyl 6-deoxy-3-O-dodecyl-6-halo-D-glucopyranoside derivatives showed powerful antimicrobial activity, but no significant differences were observed on the activity with regard to the kinds of anomers as well as halogen atoms.