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[Renal plasmacytoma]

T Kanoh1, H Katoh, T Izumi

  • 1Department of Internal Medicine, Faculty of Medicine, Kyoto University.

[Rinsho Ketsueki] the Japanese Journal of Clinical Hematology
|November 1, 1993
PubMed
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Extramedullary plasmacytoma, a rare kidney tumor, was diagnosed in a patient with prior spinal cord compression. Radiotherapy alone proved effective for the kidney plasmacytoma.

Area of Science:

  • Nephrology
  • Oncology
  • Pathology

Background:

  • Extramedullary plasmacytoma (EMP) is a rare plasma cell neoplasm occurring outside the bone marrow.
  • Renal involvement by EMP is exceptionally uncommon, with limited documented cases.

Observation:

  • A 43-year-old male presented with paraplegia due to a cervical spine plasmacytoma producing IgG-lambda paraprotein.
  • Two years post-treatment, new lesions appeared, leading to the detection of an intra-abdominal mass originating from the right kidney via Ga-67 scanning and CT.
  • Renal ultrasound revealed a solid mass with hydronephrosis, and urinary sediment showed myeloma cells, confirming renal plasmacytoma.

Findings:

  • The study reports the 12th case of renal extramedullary plasmacytoma, highlighting its rarity.
  • Diagnostic imaging and urinary cytology confirmed a solitary plasmacytoma of the kidney.

Related Experiment Videos

  • The patient's renal plasmacytoma responded successfully to radiotherapy alone.

    • Implications:

    • This case expands the understanding of extramedullary plasmacytoma presentation and diagnosis.
    • It underscores the importance of thorough investigation for extramedullary disease, even with prior bone marrow or plasma cell disorders.
    • The successful treatment with radiotherapy alone suggests its potential efficacy in managing renal plasmacytoma.