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Published on: August 15, 2025
371
[Current technical aspect in transsphenoidal pituitary adenomectomy]
1Department of Neurosurgery, Nagoya National Hospital.
Nihon Rinsho. Japanese Journal of Clinical Medicine
|October 1, 1993
Summary
This study presents surgical techniques for pituitary adenomas using transsphenoidal microsurgery. Staged removal and specific methods for microadenomas improve outcomes and preserve pituitary function.
Area of Science:
- Neurosurgery
- Endocrinology
- Oncology
Context:
- Pituitary adenomas present surgical challenges, particularly giant adenomas with suprasellar extension and small microadenomas.
- Transsphenoidal microsurgery is a key approach for pituitary tumor removal.
Purpose:
- To describe effective surgical techniques for pituitary adenomas, including giant and microadenomas.
- To detail a two-staged transsphenoidal removal approach for large tumors.
- To outline strategies for identifying and resecting small microadenomas while preserving pituitary function.
Summary:
- The authors detail a two-staged transsphenoidal removal technique for giant pituitary adenomas with suprasellar extension, involving an open sella floor and intrasellar drainage.
- This staged approach, including a second operation, achieved total selective adenomectomy in most cases without complications.
- For small microadenomas, such as those in Cushing's disease, a systematic search and precise edge resection are crucial for hormonal normalization and cure, preserving pituitary function.
Impact:
- Improved surgical outcomes for pituitary adenomas, especially large and complex cases.
- Enhanced preservation of pituitary function through tailored surgical strategies.
- Potential for increased rates of complete tumor removal and long-term cure for patients.

