Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Biosensors comprising DNA as receptive component]

M Maeda1

  • 1Department of Chemical Science and Technology, Kyushu University.

Nihon Rinsho. Japanese Journal of Clinical Medicine
|October 1, 1993
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Psychosocial approach of the epileptic patient: analysis of 30 adults].

Arquivos de neuro-psiquiatria·1992
Same author

Manganese-containing superoxide dismutase in blood and urine during open-heart surgery.

Japanese circulation journal·1992
Same author

[A case of colon angiodysplasia successfully treated with endoscopy].

Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology·1992
Same author

Occurrence of intraportally-infused urea-15N in the urine of domestic fowl.

British poultry science·1992
Same author

Escherichia coli F0F1-ATPase. Residues involved in catalysis and coupling.

Annals of the New York Academy of Sciences·1992
Same author

Studies on anticoagulant-active arabinan sulfates from the green alga, Codium latum.

Carbohydrate research·1992

DNA biosensors offer an alternative to protein-based systems for detecting DNA, ions, and DNA-binding molecules. Immobilizing DNA on solid substrates enables new sensing strategies and drug interaction analysis.

Area of Science:

  • Biochemistry
  • Molecular Biology
  • Analytical Chemistry

Context:

  • Biosensors traditionally utilize proteins like enzymes and antibodies for biological recognition.
  • DNA, in its single and double-stranded forms, presents a significant alternative as a molecular recognition element.
  • The development of DNA-based sensors is crucial for advancing biological detection technologies.

Purpose:

  • To explore methods for immobilizing DNA onto solid substrates for biosensor applications.
  • To review novel strategies for detecting analyte interactions with immobilized DNA.
  • To propose DNA duplex-modified electrodes for quantifying DNA-binding drug interactions.

Summary:

  • This article discusses coupling techniques for immobilizing DNA onto solid substrates.

Related Experiment Videos

  • It reviews innovative detection strategies for analytes interacting with immobilized DNA.
  • A DNA duplex-modified electrode is presented as a tool for determining binding constants of DNA-binding drugs.

    • Impact:

    • DNA-based biosensors provide versatile platforms for detecting complementary DNA, DNA-binding molecules, and ions.
    • Immobilization methods and detection strategies enhance the utility of DNA in biosensing.
    • The proposed DNA duplex-modified electrode offers a new approach for characterizing drug-DNA interactions.