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Stroke due to Lyme disease

L Reik1

  • 1Department of Neurology, University of Connecticut Health Center, Farmington 06030-1845.

Neurology
|December 1, 1993
PubMed
Summary

A woman experienced strokes linked to Lyme disease (neuroborreliosis) 18 months after treatment. This case highlights a rare North American stroke complication of Lyme disease.

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Area of Science:

  • Neurology
  • Infectious Diseases
  • Cardiovascular Medicine

Background:

  • Lyme disease, caused by Borrelia burgdorferi, is a tick-borne illness with diverse clinical manifestations.
  • Neuroborreliosis, the neurological form of Lyme disease, can present with various symptoms, including facial palsy.
  • Cerebrovascular events like stroke are rare complications of Lyme disease.

Observation:

  • A 56-year-old woman developed multiple strokes 18 months post-antibiotic therapy for early Lyme disease presenting with facial palsy.
  • Clinical and laboratory findings, including pleocytosis and intrathecal antibody synthesis against Borrelia burgdorferi, confirmed neuroborreliosis.

Findings:

  • The patient's stroke presentation was directly attributed to neuroborreliosis.
  • This case represents the first documented instance of stroke caused by Lyme disease acquired in North America.

Implications:

  • This case underscores the potential for delayed and severe neurological complications from Lyme disease, even after treatment.
  • Highlights the importance of considering neuroborreliosis in the differential diagnosis of stroke, particularly in endemic areas.
  • Suggests a need for further research into the mechanisms linking Lyme disease to cerebrovascular events.

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