[Prophylactic and therapeutic use of Avrazor in abdominal surgery]

The authors investigated in a group of 30 patients the prophylactic and therapeutic action of ornidazole (the Czech preparation Avrazor) injections for infusion produced by Léciva Co. Prophylactically Avrazor was used most frequently in elective colorectal surgery, therapeutically in peritonitis. In a control group comprising 30 patients with the same indications the commonly used Metronidazole was administered and the results in the two groups were compared. Avrazor was administered most frequently combined with aminoglycosides. The authors did not observe side-effects after Avrazor administration and the preparation was very well tolerated. Because of its antimicrobial effect in the prophylaxis and therapy of intraabdominal infections the preparation can be recommended for clinical use.