Beat the clock: paradigms for NTPases in the maintenance of biological fidelity
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1Department of Biochemistry and Molecular Biology, Harvard University, Cambridge, MA 02138.
Trends in Biochemical Sciences
|October 1, 1993
Abstract:
Kinetic proofreading is a strategy used by cells to reduce the number of errors made when replicating and expressing genetic information. Recent advances in mRNA splicing suggest a variation on the theme of previously described kinetic proofreading mechanisms, which may apply to other multicomponent assembly processes in the cell.