Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Aspiration pneumonia]

K B Jakobsen1, B A Schurizek

  • 1Arhus Kommunehospital, anaestesiologisk afdeling.

Ugeskrift for Laeger
|September 20, 1993
PubMed
Summary
This summary is machine-generated.

Pulmonary aspiration of stomach contents causes chemical injury and inflammation, potentially leading to secondary bacterial infection. Management focuses on immediate airway clearance, respiratory support, and antibiotics if infection is suspected.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Perioperative myocardial ischaemia in patients undergoing surgery for fractured hip randomized to incremental spinal, single-dose spinal or general anaesthesia.

European journal of anaesthesiology·1999
Same author

Extradural anaesthesia for repeated surgical treatment in the presence of infection.

British journal of anaesthesia·1995
Same author

[Diabetes and surgery--an elucidating report?].

Ugeskrift for laeger·1995
Same author

[Complications and late sequelae after nasotracheal intubation].

Ugeskrift for laeger·1994
Same author

Postoperative throat complaints after tracheal intubation.

British journal of anaesthesia·1994
Same author

[Use of colloids in acute hypovolemia].

Ugeskrift for laeger·1994
Same journal

[Mosaicism as a cause of Cowden syndrome].

Ugeskrift for laeger·2026
Same journal

[Thyrotoxic crisis with cardiogenic shock].

Ugeskrift for laeger·2026
Same journal

[Mindfulness-based cognitive therapy in the treatment of depression].

Ugeskrift for laeger·2026
Same journal

[Fitness].

Ugeskrift for laeger·2026
Same journal

[Risk of developing cataract related to fluoroscopy].

Ugeskrift for laeger·2026
Same journal

[Obturator hernia with small bowel ileus presenting as hip pain in an elderly woman].

Ugeskrift for laeger·2026
See all related articles

Area of Science:

  • Pulmonary Medicine
  • Gastroenterology
  • Critical Care

Context:

  • Pulmonary aspiration of gastric contents is a frequent clinical occurrence.
  • The severity of symptoms and outcomes are influenced by aspirate volume, acidity (pH), and presence of food particles and bacteria.

Purpose:

  • To describe the pathophysiology of pulmonary aspiration of stomach contents.
  • To outline the biphasic nature of the lung injury and associated immunological responses.
  • To detail the recommended management strategies for this condition.

Summary:

  • Pulmonary aspiration involves two phases: initial chemical injury (minutes post-aspiration) and a subsequent inflammatory reaction.
  • Acidic aspirates (pH < 2.5) trigger hemorrhagic, granulocytic, and necrotizing inflammation, while food particles can induce granulomas.

Related Experiment Videos

  • Bacterial infection, occurring in 25-50% of cases, is often secondary to the initial chemical inflammation.

    • Impact:

    • Understanding the biphasic injury mechanism aids in targeted therapeutic interventions.
    • Early and aggressive supportive care, including airway management and ventilatory support, is crucial.
    • Judicious use of antibiotics is recommended when bacterial infection is evident, optimizing patient outcomes.