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Updated: Aug 17, 2026

ALS - Motor Neuron Disease: Mechanism and Development of New Therapies
Published on: July 29, 2007
Human immunodeficiency virus-associated motor axonal polyradiculoneuropathy
J M Goldstein1, S A Azizi, J Booss
1Department of Neurology, Yale University School of Medicine, New Haven, Conn.
Objective:
To report two cases of an axonal motor polyradiculoneuropathy associated with human immunodeficiency virus infection in otherwise asymptomatic subjects.
Design:
Case series.
Setting:
Tertiary care hospital neurology inpatient service.
Results:
Electrophysiologic testing showed acute denervation with almost normal sensory potentials and no evidence of demyelination.
Conclusions:
These cases present an example of an acute axonal polyradiculoneuropathy in persons infected with human immunodeficiency virus without acquired immunodeficiency syndrome.
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