Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Chicken heterophil chemotaxis using Staphylococcus-generated chemoattractants

J R Andreasen1, C B Andreasen, M Anwer

  • 1Veterinary Diagnostic Laboratory, College of Veterinary Medicine, Oregon State University, Corvallis 97339.

Avian Diseases
|July 1, 1993
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Circulating foamy macrophages and other features of bacillus Calmette-Guérin challenge in Golden Syrian hamsters.

Vaccine·2025
Same author

A case of lung volume reduction surgery with decortication for a septic patient in respiratory failure.

International journal of surgery case reports·2015
Same author

Immune response gene expression in spleens of diverse chicken lines fed dietary immunomodulators.

Poultry science·2011
Same author

Antibodies to influenza A virus (H1 and H3) in companion animals in Iowa, USA.

The Veterinary record·2011
Same author

Differential splenic cytokine responses to dietary immune modulation by diverse chicken lines.

Poultry science·2010
Same author

Calcium-independent phospholipase A2 regulates retinal pigment epithelium proliferation and may be important in the pathogenesis of retinal diseases.

Experimental eye research·2009

Chicken heterophils showed chemotaxis in response to staphylococcal bacteria. Pathogenic Staphylococcus aureus strains induced significantly greater heterophil chemotaxis compared to nonpathogenic strains, indicating differential immune responses.

Area of Science:

  • Immunology
  • Microbiology
  • Poultry Science

Background:

  • Chicken heterophils are crucial innate immune cells.
  • Staphylococcal bacteria are common pathogens in poultry.
  • Understanding bacterial-induced immune cell migration is vital for poultry health.

Purpose of the Study:

  • To investigate heterophil chemotaxis in broiler chickens.
  • To determine the chemotactic potential of factors produced by different Staphylococcus strains.
  • To compare the immune response to pathogenic versus nonpathogenic Staphylococcus isolates.

Main Methods:

  • Modified Boyden-chamber technique used to measure heterophil chemotaxis.
  • Heterophils isolated from healthy broiler chickens (6-8 weeks old).
  • Chemotactic factors generated by three distinct Staphylococcus strains were analyzed.

Related Experiment Videos

Main Results:

  • All three tested Staphylococcus strains produced factors that attracted chicken heterophils.
  • Factors from two pathogenic Staphylococcus aureus isolates induced significantly higher heterophil chemotaxis.
  • A nonpathogenic Staphylococcus isolate generated factors with lower chemotactic activity.

Conclusions:

  • Chicken heterophils exhibit chemotaxis towards staphylococcal-derived factors.
  • Pathogenic Staphylococcus aureus strains elicit a stronger chemotactic response in chicken heterophils.
  • This differential response suggests varying immune-stimulating capacities among Staphylococcus isolates.