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Hepatic protoporphyrin accumulation in a broiler chicken
S Hafner1, D Bounous, L C Kelley
1U.S. Department of Agriculture, Food Safety and Inspection Service, Russell Research Center, Athens, Georgia 30604.
Avian Diseases
|July 1, 1993
Summary
A 6-week-old chicken liver showed significant protoporphyrin accumulation, appearing dark gray to black. Histological analysis revealed pigment granules in hepatocytes and bile ducts, characteristic of protoporphyrin.
Area of Science:
- Veterinary Pathology
- Biochemistry
- Hepatology
Background:
- Protoporphyrin is a precursor in heme synthesis.
- Abnormal accumulation can lead to health issues in animals.
- Biliary excretion is a key route for porphyrin elimination.