Risk assessment of chemical mixtures: biologic and toxicologic issues

Using available in vitro metabolite identification and time course kinetics for β-chloroprene and its metabolite, (1-chloroethenyl) oxirane, to include reactive oxidative metabolites and glutathione depletion in a PBPK model for β-chloroprene.

Frontiers in pharmacology·2023

Assessing children's exposure to manganese in drinking water using a PBPK model.

Toxicology and applied pharmacology·2019

Quantitative bias analysis of the association of type 2 diabetes mellitus with 2,2',4,4',5,5'-hexachlorobiphenyl (PCB-153).

Environment international·2019

Characterization of the effects of musk ketone on mouse hepatic cytochrome P450 enzymes.

Fundamental and applied toxicology : official journal of the Society of Toxicology·1998

Tetracycline-induced steatosis in primary canine hepatocyte cultures.

Fundamental and applied toxicology : official journal of the Society of Toxicology·1998

Tributyl phosphate effects on urine and bladder epithelium in male Sprague-Dawley rats.

Fundamental and applied toxicology : official journal of the Society of Toxicology·1998

Ketoconazole impairs early pregnancy and the decidual cell response via alterations in ovarian function.

Fundamental and applied toxicology : official journal of the Society of Toxicology·1998

Differences in caffeine 3-demethylation activity among inbred mouse strains: a comparison of hepatic Cyp1a2 gene expression between two inbred strains.

Fundamental and applied toxicology : official journal of the Society of Toxicology·1998

Intratracheal inhalation vs intratracheal instillation: differences in particle effects.

Fundamental and applied toxicology : official journal of the Society of Toxicology·1998

Breathing in harm: current insights into the effects of air pollution on cardiorespiratory health.

Medical gas research·2026

Acute graded aerobic exercise and urinary bisphenol A and triclosan in overweight postmenopausal women: a randomized pilot study.

Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering·2026

Pyrethroid Levels Amplify Asthma Severity in Children via Elevating Eosinophils, IgE, and Compromising Lung Function.

Indian journal of clinical biochemistry : IJCB·2026

Global landscape, research hotspots, and evolutionary trends in childhood adversity and chronic disease research: a bibliometric analysis based on three databases.

Frontiers in public health·2026

The New Battlefield: Food, Water, and the Evolution of Asymmetric Terror.

International journal of toxicology·2026

Exosomes in Toxicology: Emerging Biomarkers and Mechanistic Mediators of Toxicant-Induced Injury.

Journal of applied toxicology : JAT·2026

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Risk assessment of chemical mixtures: biologic and toxicologic issues

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Using available in vitro metabolite identification and time course kinetics for β-chloroprene and its metabolite, (1-chloroethenyl) oxirane, to include reactive oxidative metabolites and glutathione depletion in a PBPK model for β-chloroprene.

Assessing children's exposure to manganese in drinking water using a PBPK model.

Quantitative bias analysis of the association of type 2 diabetes mellitus with 2,2',4,4',5,5'-hexachlorobiphenyl (PCB-153).

Characterization of the effects of musk ketone on mouse hepatic cytochrome P450 enzymes.

Tetracycline-induced steatosis in primary canine hepatocyte cultures.

Tributyl phosphate effects on urine and bladder epithelium in male Sprague-Dawley rats.

Ketoconazole impairs early pregnancy and the decidual cell response via alterations in ovarian function.

Differences in caffeine 3-demethylation activity among inbred mouse strains: a comparison of hepatic Cyp1a2 gene expression between two inbred strains.

Intratracheal inhalation vs intratracheal instillation: differences in particle effects.

Breathing in harm: current insights into the effects of air pollution on cardiorespiratory health.

Acute graded aerobic exercise and urinary bisphenol A and triclosan in overweight postmenopausal women: a randomized pilot study.

Pyrethroid Levels Amplify Asthma Severity in Children via Elevating Eosinophils, IgE, and Compromising Lung Function.

Global landscape, research hotspots, and evolutionary trends in childhood adversity and chronic disease research: a bibliometric analysis based on three databases.

The New Battlefield: Food, Water, and the Evolution of Asymmetric Terror.

Exosomes in Toxicology: Emerging Biomarkers and Mechanistic Mediators of Toxicant-Induced Injury.

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Risk assessment of chemical mixtures: biologic and toxicologic issues

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