Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The phenol red thread tear test: a cross-cultural study

R Sakamoto1, E S Bennett, V A Henry

  • 1Department of Ophthalmology, Tokyo Women's Medical College, Daini Hospital, Japan.

Investigative Ophthalmology & Visual Science
|December 1, 1993
PubMed
Summary

The phenol red thread tear test revealed significant differences in tear production between US and Japanese individuals, with males showing higher tear film measurements. This easy-to-administer test may detect subtle variations in the lacrimal system.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Enhanced Material Assimilation in a Toroidal Plasma Using Mixed H_{2}+Ne Pellet Injection and Implications to ITER.

Physical review letters·2023
Same author

Electron temperature and density measurement by Thomson scattering with a high repetition rate laser of 20 kHz on LHD.

Scientific reports·2022
Same author

Absence of microsatellite instability in extramammary Paget's disease.

Skin health and disease·2022
Same author

Lactulose ingestion causes an increase in the abundance of gut-resident bifidobacteria in Japanese women: a randomised, double-blind, placebo-controlled crossover trial.

Beneficial microbes·2021
Same author

Genomic mutational profiling of circulating tumour DNA in metastatic angiosarcoma.

Journal of the European Academy of Dermatology and Venereology : JEADV·2020
Same author

Coexistence of osteoporosis and atherosclerosis in pheochromocytoma: new insights into its long-term management.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2020

Area of Science:

  • Ophthalmology
  • Physiology

Background:

  • The lacrimal system's function is crucial for ocular health.
  • Assessing tear film stability is important for diagnosing dry eye disease and other ocular surface disorders.

Purpose of the Study:

  • To conduct a cross-cultural comparison of tear film measurements using the phenol red thread test.
  • To evaluate the efficacy of the phenol red thread test in identifying subtle differences in tear production.

Main Methods:

  • A controlled study involving 1000 normal subjects (500 from the United States, 500 from Japan) who do not wear contact lenses.
  • Administration of the phenol red thread tear test to measure the wet thread length in millimeters.

Main Results:

  • Significant differences in mean wet thread length were observed between the United States (23.9 mm) and Japan (18.8 mm) (P < 0.05).

Related Experiment Videos

  • Male subjects exhibited significantly longer wet thread lengths than female subjects in both countries (P < 0.05).
  • A moderate correlation was found between right and left eye measurements within each country.

    • Conclusions:

    • The phenol red thread tear test is a simple and effective method for assessing tear production.
    • The test results align with existing knowledge of the lacrimal system.
    • This test has the potential to reveal subtle variations in tear film not detected by other methods.