Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Intracranial vertebrobasilar system: MR angiography

K U Wentz1, J Röther, A Schwartz

  • 1Division of Magnetic Resonance, Entwicklungs und Forschungszentrum für Mikrotherapie, Bochum, Germany.

Radiology
|January 1, 1994
PubMed
Summary

Magnetic resonance angiography (MRA) reliably depicts normal brain arteries and detects vertebrobasilar disease with 100% sensitivity. This noninvasive screening tool shows limitations in assessing stenosis degree but is clinically valuable.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Molecular and cellular aspects of calcium channel antagonism.

The American journal of cardiology·1992
Same author

The beta subunit controls the gating and dihydropyridine sensitivity of the skeletal muscle Ca2+ channel.

Biophysical journal·1992
Same author

Facial and trigeminal neural dysfunction by a primary cutaneous squamous cell carcinoma: MRI and clinicopathologic correlates.

The American journal of otology·1992
Same author

Analogs of CCK incorporating conformationally constrained replacements for Asp32.

Journal of medicinal chemistry·1992
Same author

Evidence for the existence of RNA of Ca(2+)-channel alpha 2/delta subunit in Xenopus oocytes.

Biochimica et biophysica acta·1992
Same author

Magnetic resonance imaging follow-up in Creutzfeldt-Jakob disease.

Journal of neurology·1992

Area of Science:

  • Neurology
  • Radiology
  • Medical Imaging

Background:

  • The vertebrobasilar system is crucial for posterior brain circulation.
  • Accurate vascular imaging is essential for diagnosing cerebrovascular diseases.
  • Digital subtraction angiography (DSA) is an invasive gold standard for vascular assessment.

Purpose of the Study:

  • To evaluate the reliability of magnetic resonance (MR) angiography in visualizing normal brain vasculature.
  • To assess the effectiveness of MR angiography in detecting vascular disease compared to DSA.
  • To determine the clinical utility of MR angiography for posterior circulation assessment.

Main Methods:

  • Sixty patients with symptoms of vertebrobasilar disease underwent both MR angiography and DSA.
  • Vascular anatomy and disease presence were compared between the two imaging modalities.

Related Experiment Videos

  • Sensitivity, specificity, and accuracy of MR angiography were analyzed.

    • Main Results:

    • MR angiography visualized all vertebral arteries (VAs) and basilar arteries (BAs) in patients with normal DSA.
    • High detection rates for superior and posterior inferior cerebellar arteries; lower for anterior inferior cerebellar arteries.
    • MR angiography demonstrated 100% sensitivity for detecting VA and BA disease, differentiating stenosis from occlusion.
    • Stenosis degree was overestimated in 63% of cases; collateral flow was accurately analyzed.

    Conclusions:

    • MR angiography is a clinically significant noninvasive method for screening posterior brain arterial supply.
    • Despite limitations in quantifying stenosis, its high sensitivity makes it valuable for initial patient assessment.
    • MR angiography aids in identifying macroangiopathy within the posterior arterial circulation.