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[Typhoid fever]

H O Fjaerli1, S G Gundersen

  • 1Infeksjonsmedisinsk avdeling, Ullevål sykehus, Oslo.

Tidsskrift for Den Norske Laegeforening : Tidsskrift for Praktisk Medicin, Ny Raekke
|October 10, 1993
PubMed
Summary
This summary is machine-generated.

Typhoid fever is rising in Norway due to increased travel. Multi-resistant strains necessitate alternative treatments like ciprofloxacin and cephalosporins, impacting future control strategies.

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Area of Science:

  • Infectious Diseases
  • Epidemiology
  • Microbiology

Context:

  • Typhoid fever cases are increasing in Norway.
  • Travel, particularly by immigrants visiting home countries, is a significant factor.
  • The study retrospectively analyzed 50 hospitalized patients.

Purpose:

  • To investigate the epidemiology, clinical presentation, diagnosis, and treatment of typhoid fever in hospitalized patients.
  • To identify trends in treatment resistance and associated clinical outcomes.

Summary:

  • Fever was the primary symptom; 13 patients had concomitant infections.
  • Standard chloramphenicol treatment was challenged by multi-resistant Salmonella typhi strains in 1990-1991.
  • Adults received ciprofloxacin, children third-generation cephalosporins; all resistant cases were linked to Pakistan or India.

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  • No secondary cases occurred among family contacts, indicating limited transmission within households.
  • Impact:

    • The rise of multi-resistant typhoid fever strains poses challenges for current treatment and public health control strategies.
    • Highlights the need for updated treatment guidelines and surveillance for infectious diseases in travelers.