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Updated: Aug 30, 2026

Development of an IFN-γ ELISpot Assay to Assess Varicella-Zoster Virus-specific Cell-mediated Immunity Following Umbilical Cord Blood Transplantation
Published on: July 9, 2014
[Transitory monoclonal gammaopathy after smallpox vaccination]
Abstract:
The case is described of a 51-year-old female who developed monoclonal gammopathy of IgMk-type following smallpox vaccination. The Mcomponent was detectable, albeit in decreasing concentrations, over a period of 10 months and then disappeared spontaneously. The findings are discussed in relation to "essential" paraproteinemia and the literature on transient monoclonal gammopathy is reviewed. This immunoglobulin abnormality may occur in a variety of disorders and has mainly been observed during infectious or inflammatory processes.
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