Related Experiment Videos
[Transitory monoclonal gammaopathy after smallpox vaccination]
Schweizerische Medizinische Wochenschrift
|June 19, 1976
Summary
A woman developed transient monoclonal gammopathy of immunoglobulin kappa-type after smallpox vaccination. This immunoglobulin abnormality resolved spontaneously within 10 months.
Area of Science:
- Immunology
- Vaccinology
Background:
- Monoclonal gammopathy is an immunoglobulin abnormality.
- It can be associated with various disorders, including infectious and inflammatory processes.
Observation:
- A 51-year-old female developed monoclonal gammopathy of immunoglobulin kappa-type (IgMk).
- This condition emerged following smallpox vaccination.
Findings:
- The M-component was detectable for 10 months, with decreasing concentrations.
- The immunoglobulin abnormality resolved spontaneously.
Implications:
- This case highlights a potential link between vaccination and transient monoclonal gammopathy.
- It contributes to the understanding of immunoglobulin abnormalities and their transient nature.