[A case of giant hepatocellular carcinoma effectively treated by UFT]

An 84-year-old woman who suffered from heart failure was admitted to our hospital in July 1991. We found a hepatocellular carcinoma, of about 9 cm in diameter in her right liver lobe. The patient could not be operated on, TAE and PEIT, so she has been administered UFT (300 mg/day) orally every day. After seven months, observing the patient by means of computerized tomography, we noticed that the tumor had decreased in size until only a small cyst was left. PIVKA-II reached the normal range (under 0.063 AU/ml) from its previous level (42.940 AU/ml). She has maintained a good state of health for about two years now. This is considered a very rare case in which chemotherapy proved to be completely effective, and the patient has survived for a long time afterwards.