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Identification of an allelic variant of isoform MLC1-V/sB (human myosin light chain)
A V Laptev1, S S Shishkin, L I Kovalyov
1Research Centre of Medical Genetics, Russian Academy of Medical Sciences, Moscow.
Biochemical Genetics
|June 1, 1993
Abstract:
A study of 250 specimens of human myocardium by two-dimensional gel electrophoresis revealed an allelic variant of isoform MLC1-V/sB, which was identified by immunoblotting with monoclonal antibody against MLC1-V/sB and peptide mapping after in situ tryptic digestion of electroblotted proteins. The substitution Asn-144 for His-144 was found in this new allelic variant of MLC1-V/sB.