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Quantitative changes in platelet counts following major urological pelvic surgery
I Leibovitch1, J Ben Chaim, G Raviv
1Department of Urology, Chaim Sheba Medical Center, Tel Hashomer, Israel.
European Urology
|January 1, 1993
Summary
Postoperative thrombocytosis, an increase in platelet counts after surgery, is common after major urological pelvic surgery. This reactive thrombocytosis is generally benign and does not increase the risk of bleeding or blood clots.
Area of Science:
- Urology
- Hematology
- Surgical Oncology
Background:
- Postoperative changes in platelet counts are observed after extensive surgeries.
- Reactive thrombocytosis below 1,000,000/mm3 is typically considered benign.
- The use of prophylactic platelet inhibitors for postoperative thrombocytosis is debated.
Purpose of the Study:
- To retrospectively analyze the timing and extent of postoperative thrombocytosis.
- To evaluate the clinical significance of thrombocytosis in major urological pelvic surgery.
- To assess the association with hemorrhagic and thromboembolic complications.
Main Methods:
- Retrospective analysis of 85 patients undergoing major urological pelvic surgery.
- Monitoring of platelet counts throughout the postoperative period.
- Identification of patient groups based on platelet count changes.
Main Results:
- 85.9% of patients showed significant postoperative platelet count changes.
- Two groups identified with early platelet decrease followed by delayed thrombocytosis.
- Thromboembolic complications occurred in 5 patients before significant platelet increase; no correlation found.
Conclusions:
- Reactive thrombocytosis is a frequent, benign finding after major urological pelvic surgery.
- Postoperative thrombocytosis is not associated with increased risk of hemorrhagic or thromboembolic complications.
- Prophylactic platelet inhibitor treatment is likely unnecessary for this condition.