[Changes in the nuclear material of the germinating conidia of Penicillium chrysogenum]

Changes in the nucleic acids during germination of the conidia were studied. It was shown that the procedure of the conidia cultivation on millet followed by vacuum drying may be considered as a means of the spore synchronization. It was found that exogenic 3H-thimidine was intensively incorporated into nucleic acids. The incorporation of the label was most intensive during the first 3 hours of incubation. Changes in the quantitative content of DNA in the conidia were also most intensive during this period, the changes being of a wave-like nature with 100-minute intervals which corresponded to the ratio of the label incorporation into the cell nucleic acids. This suggested that replication of the genetic material took place just at that period.