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Relationship between the level of c-myc mRNA and histologic aggressiveness in thyroid tumors
M I Romano1, M Grattone, M P Karner
1Department of Endocrinology, Fundación CIMAE, Hospital Israelita Ezrah, Buenos Aires, Argentina.
Hormone Research
|January 1, 1993
Abstract:
We investigated the relationship between the level of c-myc mRNA and histologic aggressiveness in thyroid tumors obtained at surgery. In thyroid carcinomas, there was a positive correlation between these two parameters, while in benign tumors there was no correlation between cellularity and the expression of the proto-oncogene c-myc. These results might be useful in the prognosis of thyroid tumors and consequently helpful in the management of the patient.