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Sequence variability of the tetranucleotide repeat of the human beta-actin related pseudogene H-beta-Ac-psi-2
A Urquhart1, C P Kimpton, P Gill
1Central Research and Support Establishment, Forensic Science Service, Aldermaston, Reading, Berks, UK.
Human Genetics
|December 1, 1993
Abstract:
Sequence analysis of polymerase chain reaction (PCR) amplified products from the presumed tetranucleotide repeat at the human beta-actin related pseudogene H-beta-Ac-psi-2 (ACTBP2) locus shows far greater variability in both PCR product length and sequence than has been previously reported. Alleles differing in size by 1 bp exist, and accurate sizing is required if the locus is to be used to its full potential.