Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cloacal exstrophy: experience with 20 cases

D P Lund1, W H Hendren

  • 1Department of Surgery, Children's Hospital, Boston, MA 02115.

Journal of Pediatric Surgery
|October 1, 1993
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Meconium staining of amniotic fluid correlates with intestinal peel formation in gastroschisis.

Pediatric surgery international·2004
Same author

Vaginal delivery after cloacal malformation repair.

Obstetrics and gynecology·2002
Same author

Appendicitis in children. New insights into an age-old problem.

JAAPA : official journal of the American Academy of Physician Assistants·2001
Same author

Nutritional morbidity in survivors of congenital diaphragmatic hernia.

Journal of pediatric surgery·2001
Same author

Life-threatening anomalies of the thoracic duct: anatomic delineation dictates management.

Journal of pediatric surgery·2001
Same author

Construction of female urethra using buccal mucosa graft.

The Journal of urology·2001
Same journal

Long-Term Growth and Neurodevelopmental Outcomes of a Standardized Gastroschisis Feeding Protocol: a retrospective cohort study.

Journal of pediatric surgery·2026
Same journal

Economic Evaluation of Hirschsprung Disease Testing Strategies for Children with Medically-Refractory Chronic Constipation: A Cost-Effectiveness Analysis.

Journal of pediatric surgery·2026
Same journal

Preoperative underweight is associated with a more complicated perioperative course and impairs recovery in Hirschsprung's disease: The pivotal role of weight-for-age z-score.

Journal of pediatric surgery·2026
Same journal

Risk Factors for Postoperative Growth Retardation in Children with Biliary Atresia After Kasai Portoenterostomy: A Retrospective Analysis.

Journal of pediatric surgery·2026
Same journal

The potential role of Daraxonrasib (RMC-6236) in relapsed neuroblastoma patients and the urgent need for preclinical investigations.

Journal of pediatric surgery·2026
Same journal

Penetrating pediatric trauma in the Netherlands: findings from the Dutch National Trauma Registry, 2015-2023.

Journal of pediatric surgery·2026
See all related articles

Cloacal exstrophy, a complex infant malformation, requires multi-stage surgical repair including bladder augmentation and continence mechanisms. Modern treatment significantly improves surgical and social outcomes for affected children.

Area of Science:

  • Pediatric Surgery
  • Developmental Biology
  • Medical Genetics

Background:

  • Cloacal exstrophy is a rare and complex congenital anomaly presenting significant challenges in infant malformations.
  • Historically, mortality rates were high, but advancements in surgical techniques have improved outcomes.

Observation:

  • The study reviewed 20 cases of cloacal exstrophy treated between 1974 and 1992, with a focus on recent management strategies.
  • Key features include omphalocele, imperforate anus, and exstrophy of hemibladders, often with gastrointestinal tract involvement.

Findings:

  • Current treatment involves omphalocele closure, separation of the gastrointestinal tract, and bladder reconstruction with augmentation (gastric augmentation preferred) and continence mechanisms.
  • Spinal cord tethering is common and often requires neurosurgical intervention.

Related Experiment Videos

  • Despite a high incidence of genetic males, gender assignment as female is recommended due to inadequate phallic development.

    • Implications:

    • Multidisciplinary surgical and neurosurgical management can lead to satisfactory functional and social outcomes for children with cloacal exstrophy.
    • Early and comprehensive intervention is crucial for improving the quality of life for these patients.
    • Further research into long-term outcomes and novel reconstructive techniques is warranted.