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Endoscopic lesions in chronic renal failure
W Ahmed1, H Qureshi, S J Zuberi
1PMRC Research Centre, Jinnah Postgraduate Medical Centre, Karachi.
Summary
Gastrointestinal lesions are common in patients with chronic renal failure (CRF). Endoscopy revealed inflammatory changes, erosions, and ulcers, with higher frequencies in advanced CRF stages and dialysis patients.
Area of Science:
- Gastroenterology
- Nephrology
- Internal Medicine
Background:
- Chronic renal failure (CRF) is a complex condition with systemic implications.
- Gastrointestinal (GI) complications are frequently observed in CRF patients.
- Understanding the spectrum of upper GI lesions in CRF is crucial for patient management.
Purpose of the Study:
- To investigate the prevalence and types of upper gastrointestinal lesions in patients with chronic renal failure.
- To correlate the occurrence of these lesions with the severity of CRF and dialysis status.
Main Methods:
- A cohort of 101 patients with chronic renal failure underwent upper gastrointestinal endoscopy.
- Lesions were categorized based on endoscopic findings.
- Data on CRF stage and dialysis treatment were collected and analyzed.
Main Results:
- Inflammatory changes were the most frequent lesions (40 cases), followed by erosions (16) and ulcers (7).
- Atrophic folds (17) and pale mucosa (11) were also noted.
- Moniliasis was observed in 6 patients, exclusively in end-stage CRF.
- Lesions were significantly more prevalent in advanced CRF (81%) and dialysis patients (79%).
Conclusions:
- Upper gastrointestinal lesions are highly prevalent in patients with chronic renal failure.
- The frequency of these lesions correlates positively with the severity of CRF and dialysis treatment.
- Endoscopic evaluation is valuable for diagnosing and managing GI complications in CRF.