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A Murine Model of Irreversible and Reversible Unilateral Ureteric Obstruction
14:05

A Murine Model of Irreversible and Reversible Unilateral Ureteric Obstruction

Published on: December 20, 2014

[Surgical correction of multiple ureter obstructions in children]

A P Erokhin, L B Menovshchikova, S L Kovarskiĭ

    Khirurgiia
    |August 1, 1993
    PubMed

    Insights

    Congenital hydronephrosis can involve double ureteral obstructions. Surgical resection and anastomosis are effective, especially with microsurgical techniques, for treating these complex cases.

    Area of Science:

    • Pediatric Urology
    • Surgical Innovation

    Background:

    • Congenital hydronephrosis frequently presents with pyeloureteral obstruction.
    • Associated distal ureteral strictures are often overlooked during initial diagnosis.

    Observation:

    • During operations for congenital hydronephrosis, 10 of 80 patients exhibited secondary distal ureteral strictures.
    • These dual obstructions were typically located 1.7-2.0 cm from the pelvioureteral junction.

    Findings:

    • Resection of the affected segment and formation of an Andersen-Haynes anastomosis proved successful in treating these double obstructions.
    • The presence of dual strictures suggests significant dysplastic changes in the ureteral wall.

    Implications:

    • Microsurgical techniques, including magnification and fine suturing, are recommended for optimal anastomosis outcomes.
    • Consideration should be given to expanding retrograde pyelography indications for improved diagnosis of additional ureteral strictures.

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