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Updated: Aug 1, 2026
05:43
Topical Airway Anesthesia for Awake-endoscopic Intubation Using the Spray-as-you-go Technique with High Oxygen Flow
Published on: January 13, 2017
[General anesthesia without nitrogen monoxide. Its use in abdominal surgery]
A Mastroianni1, M T Novelli, M Aiassa
1Servizio di Anestesia e Rianimazione, Regione Piemonte, USSL n. 30, Chieri, Torino.
Minerva Anestesiologica
|July 1, 1993
Summary
This study presents a new anesthesia protocol that avoids nitrous oxide (N2O), using higher fentanyl and isoflurane doses instead. The modified technique proved effective for abdominal surgery patients, showing satisfactory results.
Area of Science:
- Anesthesiology
- Pharmacology
Context:
- Routine use of nitrous oxide (N2O) in general anesthesia presents challenges.
- Alternative anesthetic strategies are needed to mitigate N2O-related issues.
Purpose:
- To develop and evaluate a novel anesthetic protocol that excludes nitrous oxide.
- To assess the efficacy of increased fentanyl and isoflurane doses as a replacement for N2O's analgesic effects.
Summary:
- Anesthesiological protocol excluding N2O was developed for 23 abdominal surgery patients.
- Higher doses of fentanyl and inspired isoflurane percentage were used to replace N2O's analgesic effect.
- Patient monitoring included PAOS/D, heart rate, lacrimation, and sweating.
Impact:
- The protocol demonstrated satisfactory results in nearly all patients.
- Further modifications are planned to enhance technique stability and manageability.
- This research contributes to safer anesthetic practices by exploring N2O alternatives.
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