[General anesthesia without nitrogen monoxide. Its use in abdominal surgery]
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Updated: Aug 1, 2026

Topical Airway Anesthesia for Awake-endoscopic Intubation Using the Spray-as-you-go Technique with High Oxygen Flow
Published on: January 13, 2017
A Mastroianni1, M T Novelli, M Aiassa
1Servizio di Anestesia e Rianimazione, Regione Piemonte, USSL n. 30, Chieri, Torino.
Abstract:
In view of the problems relating to the routine use of nitrogen monoxide in general anesthesia, the authors drew up an anesthesiological protocol excluding the use of N2O and replacing its analgesic effect with higher doses of fentanyl and a higher inspired percentage of isoflurane. Twenty-three patients due to undergo abdominal surgery were included in the study. The established anesthetic protocol was evaluated by the constant measurement of PAOS/D and heart rate, as well as lacrimation and sweating. Satisfactory results were achieved using this protocol in almost all patients, although further modifications to the protocol are planned to make the technique more stable and manageable.
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