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Distinct DNA binding preferences for the c-Myc/Max and Max/Max dimers

D L Solomon1, B Amati, H Land

  • 1Growth Control and Development Laboratory, Imperial Cancer Research Fund, London, UK.

Nucleic Acids Research
|November 25, 1993
PubMed
Summary

The transcription factor c-Myc/Max binds DNA poorly with certain flanking sequences, unlike Max/Max dimers. This DNA binding difference impacts gene regulation by c-Myc.

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