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Subcortical infarction in children

F C Powell1, W C Hanigan, K W McCluney

  • 1Department of Neurological Surgery, University of Illinois College of Medicine at Peoria.

Stroke
|January 1, 1994
PubMed
Summary
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Pediatric subcortical infarction, though uncommon, often presents as acute hemiparesis in children. Identified risk factors are common, and most children experience good neurological recovery.

Area of Science:

  • Neurology
  • Pediatric Neurology
  • Neuroradiology

Background:

  • Subcortical infarction is an uncommon neurological event in childhood.
  • This study reviews clinical characteristics and outcomes of pediatric subcortical infarction.
  • Literature review identifies risk factors and prognoses in affected children.

Observation:

  • Five pediatric cases of subcortical infarction were analyzed, with a mean age of 4.8 years.
  • Presentations included hemiparesis, dystonia, fever, and focal seizures.
  • Identified risk factors included Protein C deficiency and cardiomyopathy.

Findings:

  • Literature review of 79 patients revealed common risk factors like infection, trauma, and hematologic disorders.
  • Hemiplegia was the most frequent presentation (46/51 patients).

Related Experiment Videos

  • Approximately 80% of patients showed good or complete resolution of neurological deficits after follow-up.

    • Implications:

    • Subcortical infarction in children typically presents with hemiparesis.
    • Early identification of risk factors is crucial for management.
    • Prognosis is generally favorable with appropriate care and follow-up.