Fibrosarcoma: observations on the ultrastructure
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Updated: Oct 14, 2026

Ultrasonic-augmented Primary Adult Fibroblast Isolation
Published on: July 29, 2019
C H Suh1, N G Ordonez, B Mackay
1Department of Pathology, College of Medicine, Chosun University, Kwang Ju, Republic of Korea.
Abstract:
Ultrastructural observations on 60 fibrosarcomas are presented. Myofibroblastic differentiation was found in 33 tumors but usually in scattered cells. Diffuse aggregates of nonspecific intermediate filaments were present in a number of the tumors. Electron microscopy is useful to distinguish fibrosarcoma from other soft tissue sarcomas that it can resemble by routine light microscopy, and its value is enhanced when selected immunocytochemical procedures are also performed.
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