Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Fibrosarcoma: observations on the ultrastructure

C H Suh1, N G Ordonez, B Mackay

  • 1Department of Pathology, College of Medicine, Chosun University, Kwang Ju, Republic of Korea.

Ultrastructural Pathology
|May 1, 1993
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Development and validation of a deep learning-based automatic classification algorithm for the medial temporal lobe atrophy score using a multimodality cascade transformer.

Clinical radiology·2025
Same author

Efficacy and safety of shunt surgery in patients with idiopathic normal-pressure hydrocephalus: can we predict shunt response by preoperative magnetic resonance imaging (MRI)?

Clinical radiology·2024
Same author

Improved diagnostic performance of susceptibility-weighted imaging with compressed sensing-sensitivity encoding and neuromelanin-sensitive MRI for Parkinson's disease and atypical Parkinsonism.

Clinical radiology·2023
Same author

Image findings of anti-neutrophil cytoplasmic antibody-associated vasculitis involving the skull base.

Clinical radiology·2023
Same author

Detection rate of MR myelography without intrathecal gadolinium in patients with newly diagnosed spontaneous intracranial hypotension.

Clinical radiology·2022
Same author

Carotid Plaque Composition Assessed by CT Predicts Subsequent Cardiovascular Events among Subjects with Carotid Stenosis.

AJNR. American journal of neuroradiology·2021

Electron microscopy aids in distinguishing fibrosarcomas from other soft tissue sarcomas. This technique, especially when combined with immunocytochemistry, enhances diagnostic accuracy for these challenging tumors.

Area of Science:

  • Oncology
  • Pathology
  • Electron Microscopy

Background:

  • Fibrosarcomas are malignant tumors that can be challenging to diagnose.
  • Distinguishing fibrosarcomas from other soft tissue sarcomas is crucial for appropriate treatment.

Purpose of the Study:

  • To present ultrastructural observations of fibrosarcomas.
  • To evaluate the utility of electron microscopy in fibrosarcoma diagnosis.

Main Methods:

  • Ultrastructural analysis of 60 fibrosarcoma samples.
  • Evaluation of myofibroblastic differentiation and intermediate filaments.
  • Comparison with light microscopy findings.

Main Results:

  • Myofibroblastic differentiation observed in 33 tumors, often as scattered cells.

Related Experiment Videos

  • Diffuse aggregates of nonspecific intermediate filaments identified in several tumors.
  • Electron microscopy demonstrated utility in differentiating fibrosarcomas from mimics.

    • Conclusions:

    • Ultrastructural analysis is valuable for fibrosarcoma diagnosis.
    • Electron microscopy, particularly with immunocytochemistry, improves diagnostic specificity.
    • Helps differentiate fibrosarcoma from other soft tissue sarcomas.