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[Circumscribed skin necroses following intramuscular injections. Review and case reports]
Abstract:
In rare instances local hemorrhagic necroses may be observed after intramuscular injection. The clinical features of this side reaction - lividoid dermatitis progressing to hemorrhagic necrosis and prolonged wound healing - are presented in the light of four of our own observations. With regard to the etiology, functional vascular spasm, embolism or/and local thromboses are discussed.