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Related Experiment Videos

A compact and noise free electrohydraulic total artificial heart

L S Yu1, M Finnegan, S Vaughan

  • 1Abiomed, Inc., Danvers, MA 01923.

ASAIO Journal (American Society for Artificial Internal Organs : 1992)
|July 1, 1993
PubMed
Summary

The ABIOMED total artificial heart (TAH) offers a tether-free solution for end-stage heart disease. Animal and cadaver studies demonstrate its excellent anatomical fit and capacity to support high cardiac output.

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Area of Science:

  • Biomedical Engineering
  • Cardiovascular Devices
  • Surgical Technology

Background:

  • End-stage heart disease necessitates advanced circulatory support.
  • Existing artificial hearts face limitations in long-term use and anatomical compatibility.
  • The ABIOMED total artificial heart (TAH) aims to overcome these challenges.

Purpose of the Study:

  • To evaluate the design, implantation, and performance of the ABIOMED total artificial heart (TAH).
  • To assess the anatomical fit and hemodynamic capabilities of the TAH in preclinical models.

Main Methods:

  • Hydraulic fluid motion across flexing diaphragms for blood pumping.
  • Miniature centrifugal pump (50% efficiency) for hydraulic power.
  • Rotary valve for flow direction control.

Related Experiment Videos

  • Trileaflet polyetherurethane valves (24 mm) and quick connectors for implantation.
  • Atrial hydraulic shunt for left-right flow balance.

    • Main Results:

    • The TAH demonstrated excellent anatomical fit in Long Horn calves (90-100 kg) and an 85 kg cadaver.
    • Capable of achieving cardiac output exceeding 10 L/min in animal studies.
    • Designed for tether-free, long-term use.

    Conclusions:

    • The ABIOMED TAH presents a promising solution for end-stage heart failure.
    • Its design facilitates anatomical optimization and efficient hemodynamic support.
    • Preclinical studies support its potential for clinical application.