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A completely implanted left ventricular assist device. Chronic in vivo testing

W J Weiss1, G Rosenberg, A J Snyder

  • 1Department of Surgery, Pennsylvania State University, Hershey 17033.

ASAIO Journal (American Society for Artificial Internal Organs : 1992)
|July 1, 1993
PubMed
Summary

This study tested a fully implantable left ventricular assist device (LVAD) for permanent heart support. Animal trials demonstrated the feasibility of this leadless LVAD system for long-term ventricular assistance.

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Area of Science:

  • Biomedical Engineering
  • Cardiovascular Devices
  • Implantable Technology

Background:

  • Percutaneous leads in left ventricular assist devices (LVADs) pose infection risks and limit long-term use.
  • Developing a completely implantable LVAD eliminates percutaneous lead complications, offering a safer alternative for permanent circulatory support.

Purpose of the Study:

  • To evaluate the feasibility and performance of a novel, completely implantable left ventricular assist device (LVAD) system in chronic animal studies.
  • To assess the efficacy of transcutaneous energy transmission and wireless telemetry in a leadless LVAD design.

Main Methods:

  • A completely implantable LVAD featuring a brushless DC motor, rollerscrew converter, and polyurethane blood sac was implanted in six bovine subjects.
  • The system utilized transcutaneous energy transmission, wireless telemetry, and automatic pump output control based on preload.

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  • Implant durations ranged up to 244 days, with ongoing assessments for two subjects.

    • Main Results:

    • The LVAD system demonstrated successful chronic in vivo performance in bovine models.
    • The device operated effectively without percutaneous leads, utilizing transcutaneous energy transfer and wireless telemetry.
    • Implant durations reached over 200 days, indicating the potential for long-term ventricular support.

    Conclusions:

    • The Penn State completely implantable LVAD system represents a feasible solution for long-term ventricular support.
    • Eliminating percutaneous leads through transcutaneous energy and wireless telemetry enhances the safety profile of LVADs.
    • This leadless LVAD technology shows promise for advancing permanent circulatory support solutions.