Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A new finger joint prosthesis

R L Whalen1, M A Bowen, M J Sarrasin

  • 1Whalen Biomedical Incorporated, Cambridge, MA.

ASAIO Journal (American Society for Artificial Internal Organs : 1992)
|July 1, 1993
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Thoracic aortic aneurysm due to giant cell arteritis without any specific symptom].

Kyobu geka. The Japanese journal of thoracic surgery·2009
Same author

[Gigantic coronary aneurysm arisen from coronary fistula between the left circumflex artery and the left ventricle].

Kyobu geka. The Japanese journal of thoracic surgery·2008
Same author

High circulating levels of soluble scavenger receptors (sCD5 and sCD6) in patients with primary Sjögren's syndrome.

Rheumatology (Oxford, England)·2001
Same author

Temperature and perfusion responses of muscle and lung tissue during chronic heating in vivo.

Medical & biological engineering & computing·2001
Same author

CD5 signal transduction: positive or negative modulation of antigen receptor signaling.

Critical reviews in immunology·2000
Same author

Particle image velocimetry investigation of intravalvular flow fields of a bileaflet mechanical heart valve in a pulsatile flow.

The Journal of heart valve disease·2000
Same journal

Machine Learning Prediction of Pediatric In-Hospital Survival Before Extracorporeal Membrane Oxygenation Cannulation.

ASAIO journal (American Society for Artificial Internal Organs : 1992)·2026
Same journal

Erratum: Safety and Efficacy of Stored Wet-Preprimed Extracorporeal Membrane Oxygenation Circuits: A Scoping Review.

ASAIO journal (American Society for Artificial Internal Organs : 1992)·2026
Same journal

Case Series of Extracorporeal Cardiopulmonary Resuscitation for Refractory Cardiopulmonary Arrest After Cardiac Surgery.

ASAIO journal (American Society for Artificial Internal Organs : 1992)·2026
Same journal

Association Between Veno-Venous Extracorporeal Membrane Oxygenation and Right Ventricular Dysfunction in Acute Respiratory Distress Syndrome Patients: A Multicenter Retrospective Propensity-Matched Study.

ASAIO journal (American Society for Artificial Internal Organs : 1992)·2026
Same journal

Prolonged Mechanical Circulatory Support of Neonatal Biventricular Failure via Single Ventricle Conversion With Ventricular Assist Device.

ASAIO journal (American Society for Artificial Internal Organs : 1992)·2026
Same journal

Redefining Limits: Extracorporeal Cardiopulmonary Resuscitation in Adult Thrombotic Thrombocytopenic Purpura.

ASAIO journal (American Society for Artificial Internal Organs : 1992)·2026
See all related articles

A novel finger joint prosthesis with a mechanical hinge and protective jacket shows promise for improved joint function. In vivo tests demonstrated reduced fibrous tissue capsule formation, suggesting better long-term outcomes for this new implant design.

Area of Science:

  • Biomedical Engineering
  • Orthopedic Surgery
  • Materials Science

Background:

  • Current finger joint prostheses offer limited long-term function.
  • A new prosthesis design aims to improve upon existing joint spacer limitations.

Purpose of the Study:

  • To develop and evaluate a novel finger joint prosthesis with a mechanical hinge and elastomeric jacket.
  • To assess the in vivo efficacy of the new prosthesis design in reducing fibrous tissue capsule formation.

Main Methods:

  • The prosthesis is fabricated from titanium alloy (6A14V) with high-density polyethylene bearings and a sealed elastomeric jacket.
  • In vitro flexure tests exceeded 75 million cycles without failure.
  • In vivo study involved implanting jacketed and unjacketed prostheses in rabbit knee joints for 8 weeks, followed by histological analysis.

Related Experiment Videos

Main Results:

  • In vitro tests confirmed the durability of the hinge mechanism.
  • In vivo results showed a significantly reduced fibrous tissue capsule thickness around jacketed implants (1.5 mm) compared to controls (4.5 mm).
  • Both groups experienced a progressive loss in range of motion, indicating areas for future design improvement.

Conclusions:

  • The novel finger joint prosthesis with a jacketed hinge mechanism demonstrates potential for improved biocompatibility and reduced soft tissue response.
  • Further research is warranted to optimize range of motion and long-term functional outcomes.