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Portable data acquisition and control apparatus for implanted drug infusion pump interrogation

A S Cress1, B D Wigness, F D Dorman

  • 1Division of Biomedical Engineering, University of Minnesota, Minneapolis 55455.

ASAIO Journal (American Society for Artificial Internal Organs : 1992)
|July 1, 1993
PubMed
Summary

Diagnosing implantable drug infusion pump failures is crucial. A new portable device monitors pump performance by measuring reservoir pressure during refills, simplifying failure detection.

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Area of Science:

  • Biomedical Engineering
  • Medical Device Technology
  • Drug Delivery Systems

Background:

  • Implantable drug infusion pumps are widely used clinically.
  • Methods for diagnosing suspected pump failures are needed.
  • Previous benchtop apparatus was cumbersome for in vivo monitoring.

Purpose of the Study:

  • To develop a portable apparatus for diagnosing implantable drug infusion pump failures.
  • To provide a simpler and more accessible method for in vivo pump monitoring.

Main Methods:

  • A portable interrogation unit was created, comprising a laptop computer, data acquisition software, an analog/ASCII interface, a pressure transducer, and fluid conduits.
  • Communication with the implanted pump is achieved via percutaneous needle puncture of the drug reservoir refill septum.

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  • Pump performance is assessed by incrementally filling the reservoir and simultaneously measuring reservoir pressure.
  • Main Results:

    • The apparatus generates a real-time plot of pressure versus volume.
    • This pressure-volume plot quickly identifies or rules out reservoir pressure as a failure mode.
    • Diagnostic runs are saved for archival purposes.

    Conclusions:

    • The portable pump interrogation apparatus offers a practical solution for diagnosing implantable drug infusion pump failures.
    • This device is expected to be as beneficial as the previously developed benchtop apparatus for pump technology development and clinical use.