Related Experiment Videos
Relationship of IL-2, IL-2R (CD25+), soluble IL-2R and IL-4 with disease activity in SLE patients
M J Cuadrado1, M Marubayashi, C Ortega
1Unit of Rheumatology, Hospital Universitario Reina Sofia, Facultad de Medicina, Universidad de Cordoba, Spain.
Lupus
|August 1, 1993
Abstract:
The plasma levels of interleukin-4 (IL-4), interleukin-2 (IL-2), soluble receptor of IL-2 (IL-2R) and T cell expression of IL-2 receptor chain (CD25+) were determined in an attempt to relate these parameters with disease activity in systemic lupus erythematosus (SLE). IL-4, IL-2 and sIL-2R plasma levels of SLE patients were significantly higher than those of the control group (P < 0.05) while CD25+ expression was similar in both groups. Only sIL-2R levels were significantly higher (P < 0.05) in active than in inactive patients.