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[Essential fatty acids in neonates at risk and in the mother's milk]
J Mourek1, A Mydlilová, J Base
1Fyziologický ústav 1. lékarské fakulty UK, Praha.
Insights
Essential fatty acids are crucial for newborns. This study found deficits in risk newborns and certain maternal milk samples, highlighting the need for targeted nutritional therapy.
Area of Science:
- Biochemistry
- Neonatal Nutrition
- Pediatrics
Context:
- Essential fatty acids (EFAs) are vital for infant development.
- Neonatal health is significantly influenced by EFA levels.
- Risk newborns often face nutritional challenges.
Purpose:
- To compare EFA profiles in healthy and at-risk neonates.
- To analyze EFA content in human milk from various maternal conditions.
- To evaluate EFA levels in infant formulas and milk banks.
Summary:
- EFA levels were assessed in healthy neonates, premature infants (with and without tocolytic therapy), and hypotrophic newborns.
- Maternal milk from healthy mothers, those with preterm delivery, and diabetic mothers were analyzed.
- EFA concentrations in Feminar formula and banked milk were also determined.
Impact:
- Identified significant EFA deficits in specific at-risk newborn groups.
- Revealed EFA deficiencies in milk from mothers with preterm delivery and diabetes, and in certain commercial products.
- Findings support the development of evidence-based nutritional interventions for vulnerable neonates.
Abstract:
The participation of essential fatty acids and their derivatives in the blood (serum) of physiological healthy neonates (physiological pregnancy, physiological delivery) is compared with the spectrum of essential fatty acids of risk newborns (prematurity, prematurity with the tocolytic therapy and hypotrophic newborns). In the following part the presence and participation of essential fatty acids in the human maternal milk were measured. The milk of healthy mothers, of mothers with preterm delivery (37 week of gestation), of diabetic mothers were mutually compared and finally the values of mentioned essential fatty acids in formula Feminar and in the milk from the bank were established. As a consequence of our observations, they point out the absence or serious deficit of some essential fatty acids in certain groups of risk newborns as well as in the milk of diabetic mothers, of mothers with preterm delivery and in Feminar and Milk-bank. The presented facts--after their opinion--could be well judged as a rational basis for adequate nutritional therapy in risk newborns.