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Pulmonary function in diabetic children with and without persistent microalbuminuria

A Verrotti1, M Verini, F Chiarelli

  • 1University Department of Pediatrics, Ospedale Pediatrico, Chieti, Italy.

Diabetes Research and Clinical Practice
|August 1, 1993
PubMed
Summary

Diabetic children and adolescents showed normal lung function, even with microalbuminuria. This suggests microalbuminuria is not a risk factor for abnormal pulmonary function in this population.

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Area of Science:

  • Pediatric Endocrinology
  • Pulmonary Medicine
  • Nephrology

Background:

  • Diabetes mellitus in children and adolescents can lead to various complications.
  • Microalbuminuria is an early marker of diabetic nephropathy.
  • Pulmonary function abnormalities have been reported in adults with diabetes.

Purpose of the Study:

  • To evaluate the pulmonary function in diabetic children and adolescents.
  • To determine if microalbuminuria is associated with abnormal lung function in this cohort.

Main Methods:

  • Spirometry and plethysmography were used to assess lung function.
  • 68 diabetic children and adolescents (aged 6.01–22.00 years) were studied.
  • Patients were assessed basally and after the Bruce exercise test.

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Main Results:

  • All spirometric and plethysmographic parameters were normal in all participants.
  • Pulmonary function remained normal regardless of the presence or absence of microalbuminuria.
  • Duration of diabetes ranged from 1 to 247 months.

Conclusions:

  • Microalbuminuria does not appear to be a risk factor for developing abnormal pulmonary function in diabetic children and adolescents.
  • Lung function is generally preserved in pediatric diabetic patients, even with early signs of kidney damage.