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Pulmonary function in diabetic children with and without persistent microalbuminuria
A Verrotti1, M Verini, F Chiarelli
1University Department of Pediatrics, Ospedale Pediatrico, Chieti, Italy.
Insights
Diabetic children and adolescents showed normal lung function, even with microalbuminuria. This suggests microalbuminuria is not a risk factor for abnormal pulmonary function in this population.
Area of Science:
- Pediatric Endocrinology
- Pulmonary Medicine
- Nephrology
Background:
- Diabetes mellitus in children and adolescents can lead to various complications.
- Microalbuminuria is an early marker of diabetic nephropathy.
- Pulmonary function abnormalities have been reported in adults with diabetes.
Purpose of the Study:
- To evaluate the pulmonary function in diabetic children and adolescents.
- To determine if microalbuminuria is associated with abnormal lung function in this cohort.
Main Methods:
- Spirometry and plethysmography were used to assess lung function.
- 68 diabetic children and adolescents (aged 6.01–22.00 years) were studied.
- Patients were assessed basally and after the Bruce exercise test.
Main Results:
- All spirometric and plethysmographic parameters were normal in all participants.
- Pulmonary function remained normal regardless of the presence or absence of microalbuminuria.
- Duration of diabetes ranged from 1 to 247 months.
Conclusions:
- Microalbuminuria does not appear to be a risk factor for developing abnormal pulmonary function in diabetic children and adolescents.
- Lung function is generally preserved in pediatric diabetic patients, even with early signs of kidney damage.
Abstract:
The principal spirometric and plethysmographic parameters were measured in 68 (38 female) diabetic children and adolescents, aged from 6.01 to 22.00 years; their duration of disease ranged from 1 to 247 months. Thirty-four patients had persistent microalbuminuria. The patients were studied basally and after the Bruce test. All the spirometric parameters were normal in all children, with and without microalbuminuria. The presence of microalbuminuria seems not to be a risk factor for the developing of abnormal pulmonary function.