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Male breast tumours

Z Sulyok1, I Köves

  • 1Department of Surgery, National Institute of Oncology, Budapest, Hungary.

European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
|December 1, 1993
PubMed
Summary

This study on male breast cancer highlights that lymph node status significantly impacts survival. Early treatment and hormone receptor status are crucial for effective management and improved patient outcomes.

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Area of Science:

  • Oncology
  • Surgical Oncology
  • Endocrinology

Background:

  • Male breast cancer is rare, necessitating specific clinical data analysis.
  • Treatment strategies and prognostic factors require ongoing investigation.

Purpose of the Study:

  • To analyze treatment outcomes and prognostic factors in male breast cancer patients.
  • To evaluate the role of lymph node status and hormone receptors in male breast cancer.

Main Methods:

  • Retrospective analysis of 63 male breast cancer patients treated between 1967 and 1990.
  • Surgical treatment included mastectomy and axillary block dissection.
  • Steroid hormone receptor analysis was performed on a subset of patients since 1980.

Main Results:

  • Lymph node status was a primary determinant of prognosis, with node-negative patients surviving longer (116 months vs. 38.9 months).
  • Metastases occurred in 61% of cases, and local recurrence in 14%.
  • Estrogen receptor positivity was high (25/27 patients), indicating hormonal influence.

Conclusions:

  • Timely treatment and lymph node assessment are critical for male breast cancer prognosis.
  • Hormone receptor status provides valuable information for treatment planning.
  • Combined hormone and cytostatic therapy may prolong survival in advanced cases.

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