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Effect of vitamin-E on high fat diet induced hyperlipidemia in rats
R Manimegalai1, A Geetha, K Rajalakshmi
1Department of Biochemistry, Bharathi Women's College, North Madras, India.
Indian Journal of Experimental Biology
|August 1, 1993
Abstract:
High fat diet intake in rats resulted in hyperlipidemia which was evidenced by elevated levels of plasma cholesterol, free fatty acids, triglycerides and increased LDLc/HDLc ratio. Vitamin E (400 mg/kg body wt/day) administration for 60 days prevented the elevations in plasma lipid levels. It reduced LDLc/HDLc ratio, lipid peroxide levels and elevated the level of reduced glutathione (GSH) in hyperlipidemic rats. Vitamin-E was non-toxic.